Welcome to the Baifeng Home
My name is Baifeng Zhang (B. Zhang).
I was graduated with bachelor degree from Ningbo University (NBU) and majored in molecular biology. I have excellent command of PCR, Primer design, Constructed vector, Connection, Conversion and Coated plates etc. During my study in NBU, I successfully developed a molecular diagnostic assay, which can be used to detect the potential microcystin-producing Microcystis in the aquatic ecosystem. I actively participated in several projects with peer-reviewed papers published on Harmful Algae, Acta Ecologica Sinica.
Since 2013, I started my journey as a Bioinformatics Engineer in BGI, and then leaded several large-scale projects analyzing the whole genome, whole exome, RNA-seq and DNA methylation sequencing data from renal cancer (Nature Communications), bladder cancer, ovarian cancer (Gynecologic Oncology)and nasopharyngeal carcinoma patients.
At 2018, I moved to Karolinska Institutet as a researh assistant of Zongli Zheng’s group and focused on a clinical-grade fusion detection algorithm with high research potentials (SplitFusion).
Now, I am pursuing my PhD degree under the joint-supervision of Prof. Xinyuan Guan (academical) and Prof. Dora Lai-wan KWONG (clinical), from Department of Clinical Oncology in Li Ka Shing Faculty of Medicine, The University of Hong Kong (HKUMed).
I am focusing on Cancer evolution, Immunology, and Deep learning (more info) !
News
10. October 2023Congratulation! Baifeng's the co-first authored paper entitled Targeting MFGE8 secreted by cancer-associated fibroblasts blocks angiogenesis and metastasis in esophageal squamous cell carcinoma is published in PNAS!
14-16. June 2023Baifeng is invited to give a short talk on Metastatic microenvironment of ESCC in IAS International Workshop on Biological data science, AI & Medicine (BAM workshop) hosted by HKUST IAS (June 14-16)
14-19. April 2023Baifeng is selected for poster presentation on Pan-cancer single-cell analysis reveals the interactions of SPP1+MMP12+ macrophages with metastasis-initiating cells that drives metastasis in AACR Annual Meeting 2023 in Orlando, Florida (April 14-19)
29. January 2023Congratulation! Baifeng's the co-first authored paper entitled Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma is published in Advanced Science!
24. January 2023Congratulation! Baifeng's the co-authored paper entitled Enhanced mitophagy driven by ADAR1-GLI1 editing supports the self-renewal of cancer stem cells in hepatocellular carcinoma is published in Hepatology!
10. December 2022Congratulation! Baifeng's the corresponding-authored paper entitled Integrated analysis of racial disparities in genomic architecture identifies a trans-ancestry prognostic subtype in bladder cancer is published in Molecular Oncology!
26. November 2022Congratulation! Baifeng's the corresponding-authored paper entitled A prognostic risk model for glioma patients by systematic evaluation of genomic variations is published in iScience!
29. September 2022Congratulation! Baifeng's the co-authored paper entitled Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer is published in Journal of Experimental & Clinical Cancer Research!
25. May 2022Congratulation! Baifeng's the co-authored paper entitled Targeting TROY-mediated P85a/AKT/TBX3 signaling attenuates tumor stemness and elevates treatment response in hepatocellular carcinoma is published in Journal of Experimental & Clinical Cancer Research!